Diagnosing Hypothyroidism

How is Hypothyroidism diagnosed?

This along with a physical exam & laboratory blood tests allow for an accurate diagnosis to be made.6

Thyroid Blood Tests Your Clinician May Consider:

1. Thyroid Stimulating Hormone (TSH)2,6

  • Most sensitive test to screen for hypothyroidism
  • TSH level is elevated when the thyroid gland does not make enough thyroid hormone

2. Free Thyroxine (T4)2

  • Measures the Free T4 in the blood that is unattached to proteins, which is what your body’s cells use.

3. Free Triiodothyronine (T3)

  • Measures the Free T3 in the blood that is unattached to proteins.

4. Thyroid Autoantibodies2,6

  • Detects anti-thyroid antibodies that attack the thyroid
  • Indicates the likelihood of autoimmune thyroiditis

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Citations: 1. Harvard Medical School. Thyroid Disorders. Fort Dodge: Harvard Medical School, n.d. Patient Education Center. Harvard Medical School. Web. 14 Feb. 2017. 2. American College of Endocrinology. Hypothyroidism. 2016. http://www.thyroidawareness.com/sites/all/ les/hypothyroidism.pdf. Accessed February 14, 2017. 3. Vandenpump MPJ. The epidemiology of thyroid disease. Br Med Bull. 2011;94:39-51. 4. DeGroot L, Abalovich M, Alexander EK, et al. Management of thyroid dysfunction during pregnancy and postpartum: An Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2012;97:2543-2565. 5. Baskin HJ, Cobin RH, Duick DS, et al. American Association of Clinical Endocrinologists medical guidelines for clinical practice for the evaluation and treatment of hyperthyroidism and hypothyroidism. Endocr Pract. 2002;8:458-467. 6. Hormonal Health Network. Hypothyroidism Fact Sheet. N.p.: Hormonal Health Network, n.d. Hormone. Endocrine Society, Mar. 2010. Web. 14 Feb. 2017. 7. Jonklaas J, Bianco AC, Bauer AJ, et al. Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement. Thyroid. 2014;24(12):1670-1751. doi:10.1089/thy.2014.0028. 8. Wiersinga WM, Duntas L, Fadeyev V, Nygaard B, Vanderpump MPJ. 2012 ETA Guidelines: The Use of L-T4 + L-T3 in the Treatment of Hypothyroidism. European Thyroid Journal. 2012; 1(2):55-71. doi10.1159/000339444. 9. Duntas L, Wartofsky L. There is no ‘Universal Fit’: Reactions on the use of L-triiodothyronine in the treatment of Hypothyroidism. Metabolism – Clinical and Experimental. 2016;65(4):428-431. 10. Gullo D, Latina A, Frasca F, Le Moli R, Pellegriti G, et al. (2011) Levothyroxine Monotherapy Cannot Guarantee Euthyroidism in All Athyreotic Patients. PLOS ONE 6(8): e22552. doi: 10.1371/journal.pone.0022552. 11. Hoang TD et al, Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: A randomized, double-blind, crossover study. J Clin Endocrinol Metab 2013; 98:1982-90. Epub March 28, 2013. 12. Hennessey, JV. (2015) Historical and Current Perspective in the use of thyroid extracts for the treatment of Hypothyroidism. Endocrine Practice: October 2015, Vol. 21, No. 10, pp. 1161-1170.

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