NP Thyroid® is the #1 Prescribed DTE^
NP Thyroid® is the #1 Prescribed DTE^

Frequently Asked Questions

NP Thyroid® (thyroid tablets, USP) is indicated1:

  • As a replacement or supplemental therapy in patients with hypothyroidism of any etiology, except transient hypothyroidism during the recovery phase of subacute thyroiditis. This category includes cretinism, myxedema, and ordinary hypothyroidism in patients of any age (children, adults, the elderly), or state (including pregnancy); primary hypothyroidism resulting from functional deficiency, primary atrophy, partial or total absence of thyroid gland, or the effects of surgery, radiation, or drugs, with or without the presence of goiter; and secondary (pituitary), or tertiary (hypothalamic) hypothyroidism
  • As a pituitary thyroid-stimulating hormone (TSH) suppressant, in the treatment or prevention of various types of euthyroid goiters, including thyroid nodules, subacute or chronic Iymphocytic thyroiditis (Hashimoto’s), multinodular goiter, and in the management of thyroid cancer
  • Click here to view Important Risk Information

NP Thyroid® is covered by most insurance plans and available at a low-tier out-of-pocket cost for most commercially insured.2

Cash-pay patients may pay as little as $25 for a 30-day supply and $60 for a 90-day supply. Learn more by visiting Find Savings.

NP Thyroid® is a desiccated thyroid extract (DTE) therapy containing thyroxine (T4) and triiodothyronine (T3) in one pill. NP Thyroid® is naturally-derived* from dried porcine thyroid glands.

*Naturally-derived refers to the biological nature of the porcine-derived desiccated thyroid ingredient found in the product.1

Yes. NP Thyroid® is available by prescription only. To find a provider who treats thyroid conditions, click here.

NP Thyroid® contains no ingredient made from a gluten-containing grain (wheat, barley or rye).1

The active ingredient in NP Thyroid® is desiccated thyroid extract (DTE), which contains both thyroxine (T4) and T3 (triiodothyronine). Inactive ingredients include calcium stearate, dextrose, and mineral oil.1

NP Thyroid® should be taken as prescribed by your provider.

Currently, NP Thyroid® is only available in the United States.

Select U.S. pharmacies may be substituting NP Thyroid® prescriptions with an alternative Desiccated Thyroid Extract (DTE) product. NP Thyroid® tablets are tan in color and are debossed with the letters AP.

If you are having an issue obtaining your NP Thyroid® branded prescription from your preferred pharmacy, please ask your provider to write “Dispense as Written” or “Brand Medically Necessary” on your prescription; or, consider switching your prescription to an alternative pharmacy.

NP Thyroid® may be also be filled, consistently and conveniently, via mail order through Glendale Pharmacy for as little as $25 cash. Learn more here.

All strengths of NP Thyroid® are available to U.S. retail, independent and mail order pharmacies through their wholesaler.

If your pharmacy states that NP Thyroid® is not available, please have them check with their wholesaler and request to place an order. In most cases, NP Thyroid® can be available within 24 hours or by the next business day. You can download wholesale ordering information here.

If you are still have trouble obtaining NP Thyroid® at the pharmacy, please visit our Products Update page for additional suggestions.

NP Thyroid® is widely available at retail, independent and mail order pharmacies. In some cases, pharmacies will not have a particular product or strength on their shelf and they may say that NP Thyroid® is out of stock. That does not mean that they can not order the product. Please request your pharmacy to order NP Thyroid® from their wholesaler which, in most cases, can be available the next business day.

If you are still having trouble obtaining NP Thyroid® at the pharmacy, please visit our Products Update page for additional suggestions.

Customer service can be reached at 1-800-541-4802, Monday - Thursday 8:30 am - 5:00 pm EST and Fridays 8:30 am - 1:00 pm EST. You can also reach customer service by email at [email protected].

Please click here to contact us with your question.

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Note that DTE products, including NP Thyroid®, have not been reviewed by the FDA for safety or efficacy.

IMPORTANT RISK INFORMATION, INCLUDING BOXED WARNING & INDICATIONS
Important Risk Information 

Drugs with thyroid hormone activity, alone or together with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects.
  • NP Thyroid® is contraindicated in patients with uncorrected adrenal insufficiency, untreated thyrotoxicosis, and hypersensitivity to any component of the product.
  • In the elderly and in patients with cardiovascular disease, NP Thyroid® should be used with greater caution than younger patients or those without cardiovascular disease.
  • Use of NP Thyroid® in patients with diabetes mellitus or adrenal cortical insufficiency may worsen the intensity of their symptoms.
  • The therapy of myxedema coma requires simultaneous administration of glucocorticoids.
  • Concomitant use of NP Thyroid® with oral anticoagulants alters the sensitivity of oral anticoagulants. Prothrombin time should be closely monitored in thyroid-treated patients on oral anticoagulants.
  • In infants, excessive doses of NP Thyroid® may produce craniosynostosis.
  • Partial loss of hair may be experienced by children in the first few months of therapy but is usually transient.
  • Adverse reactions associated with NP Thyroid® therapy are primarily those of hyperthyroidism due to therapeutic overdosage.
  • Many drugs and some laboratory tests may alter the therapeutic response to NP Thyroid®. In addition, thyroid hormones and thyroid status have varied effects on the pharmacokinetics and actions of other drugs. Administer at least 4 hours before or after drugs that are known to interfere with absorption. Evaluate the need for dose adjustments when regularly administering within one hour of certain foods that may affect absorption.
  • NP Thyroid® should not be discontinued during pregnancy, and hypothyroidism diagnosed during pregnancy should be promptly treated.

Indications

NP Thyroid® (thyroid tablets, USP) is a prescription medicine that is used to treat a condition called hypothyroidism from any cause, except for cases of temporary hypothyroidism, which is usually associated with an inflammation of the thyroid (thyroiditis). It is meant to replace or supplement a hormone that is usually made by your thyroid gland.

NP Thyroid® is also used in the treatment and prevention of normal functioning thyroid goiters, such as thyroid nodules, Hashimoto’s thyroiditis, multinodular goiter, and in the management of thyroid cancer.

Revised 10/2023