Frequently Asked Questions

NP Thyroid® tablets (thyroid tablets, USP) are indicated:

  • As replacement or supplemental therapy in patients with hypothyroidism of any etiology, except transient hypothyroidism during the recovery phase of subacute thyroiditis. This category includes cretinism, myxedema, and ordinary hypothyroidism in patients of any age (children, adults, the elderly), or state (including pregnancy); primary hypothyroidism resulting from functional deficiency, primary atrophy, partial or total absence of thyroid gland, or the effects of surgery, radiation, or drugs, with or without the presence of goiter; and secondary (pituitary), or tertiary (hypothalamic) hypothyroidism
  • As pituitary TSH suppressants, in the treatment or prevention of various types of euthyroid goiters, including thyroid nodules, subacute or chronic Iymphocytic thyroiditis (Hashimoto’s), multinodular goiter, and in the management of thyroid cancer
  • Click here to view Important Safety Information

Prices depend on strength and vary by pharmacy. To find prices in your area click here.

NP Thyroid® is a natural* preparation derived from dried porcine thyroid glands. Thyroid USP (desiccated porcine thyroid extract) is the active ingredient.

NP Thyroid® active ingredients are similar from tablet to tablet and include T4 (levothyroxine) and T3 (triiodothyronine). T4 and T3 is found in a 4:1 ratio. 60 mg of NP Thyroid® contains 38 mcg of T4 and 9 mcg of T3.

Yes. NP Thyroid® is available by prescription only. To find a thyroid doctor in your area, click here.

NP Thyroid® contains no ingredient made from a gluten-containing grain (wheat, barley or rye).

The active ingredient in NP Thyroid® is desiccated thyroid extract which contains both T4 and T3. Inactive ingredients include calcium stearate, dextrose, and mineral oil.

Currently NP Thyroid® is only available in the United States.

NP Thyroid® should be used as prescribed by your doctor.

All strengths of NP Thyroid® are available to U.S. retail pharmacies through their wholesaler. The allocation of NP Thyroid® from early 2019 has been resolved and we have increased availability of all strengths to our customers starting in July 2019.

If your pharmacy states that NP Thyroid® is not available, please have them check their wholesaler and request to place an order. In most cases, NP Thyroid® can be available within 24 hours or by the next business day. You can download wholesale ordering information here.

If you are still have trouble obtaining NP Thyroid® at the pharmacy, download our Pharmacy Checklist.

Often pharmacies will not have a particular product or strength on their shelf and they may say that NP Thyroid® is out of stock. That does not mean that they can not order the product. Please request your pharmacy to order NP Thyroid® from their wholesaler which can be available the next business day in most cases.

Our customer service line is 1-800-541-4802. Monday – Thursday 8:30 am – 5:00 pm and Fridays 8:30 am – 1:00 pm. You can also reach us by email at [email protected] or [email protected].

In order to ensure that a pharmacy does not switch your prescriptions, please make sure your doctor writes “Dispense as Written” or “Brand Medically Necessary” on your prescription. Alternately, if your pharmacy does not have NP Thyroid® in stock, give us a call at 1-800-541-4802 and we can speak with them directly. You may also choose to download our pharmacy wholesaler information to bring to your pharmacy!

Please click here to contact us with your question.

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Updates on NP Thyroid®.
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Note that DTE products, including NP Thyroid®, have not been reviewed by the FDA for safety or efficacy.

Important Risk Information

Drugs with thyroid hormone activity, alone or together with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects.
  • NP Thyroid® is contraindicated in patients with uncorrected adrenal insufficiency, untreated thyrotoxicosis, and hypersensitivity to any component of the product.
  • In the elderly and in patients with cardiovascular disease, NP Thyroid® should be used with greater caution than younger patients or those without cardiovascular disease.
  • Use of NP Thyroid® in patients with diabetes mellitus or adrenal cortical insufficiency may worsen the intensity of their symptoms.
  • The therapy of myxedema coma requires simultaneous administration of glucocorticoids.
  • Concomitant use of NP Thyroid® with oral anticoagulants alters the sensitivity of oral anticoagulants. Prothrombin time should be closely monitored in thyroid-treated patients on oral anticoagulants.
  • In infants, excessive doses of NP Thyroid® may produce craniosynostosis.
  • Partial loss of hair may be experienced by children in the first few months of therapy but is usually transient.
  • Adverse reactions associated with NP Thyroid® therapy are primarily those of hyperthyroidism due to therapeutic overdosage.
  • Many drugs and some laboratory tests may alter the therapeutic response to NP Thyroid®. In addition, thyroid hormones and thyroid status have varied effects on the pharmacokinetics and actions of other drugs. Administer at least 4 hours before or after drugs that are known to interfere with absorption. Evaluate the need for dose adjustments when regularly administering within one hour of certain foods that may affect absorption.
  • NP Thyroid® should not be discontinued during pregnancy, and hypothyroidism diagnosed during pregnancy should be promptly treated.


NP Thyroid® (thyroid tablets, USP) is a prescription medicine that is used to treat a condition called hypothyroidism from any cause, except for cases of temporary hypothyroidism, which is usually associated with an inflammation of the thyroid (thyroiditis). It is meant to replace or supplement a hormone that is usually made by your thyroid gland.

NP Thyroid® is also used in the treatment and prevention of normal functioning thyroid goiters, such as thyroid nodules, Hashimoto’s thyroiditis, multinodular goiter, and in the management of thyroid cancer.

Revised 10/2023