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Management Strategies for Swelling and Inflammation

Acella Pharmaceuticals is partnering with Angila Berni, M.S., CPT, SFG II, RYT to bring greater awareness to the importance of thyroid care and education. This post is sponsored by Acella Pharmaceuticals.

Disclaimer: The information provided is for educational purposes only and does not substitute professional medical advice. Consult a medical professional or healthcare provider if you believe you need medical treatment or before beginning any exercise, fitness, diet, or nutrition routine. Acella Pharmaceuticals does not endorse, promote or sponsor any products or brands mentioned in this article. The views expressed are those of the author.

People living with hypothyroidism may experience a wide range of symptoms including swelling and inflammation.1 These symptoms can be uncomfortable and painful. Managing swelling and inflammation is important as, if left unaddressed, they can actually worsen symptoms and contribute to other health complications.

Successful hypothyroidism management involves a strategic approach that addresses the underlying hormone deficiency, reduces inflammation, and improves overall health. Some strategies to be considered are pharmacologic treatments, lifestyle modification through exercise, and dietary interventions.

  1. Medication. Thyroid hormones play a role in regulating inflammation and oxidative stress.1 Management begins with working with a healthcare provider to monitor and adjust thyroid hormone levels through pharmacologic treatments. Because swelling and inflammation may also be related to other conditions, it’s important to discuss medication recommendations with your healthcare provider.
  2. Exercise. Regular exercise such as walking, swimming, or biking improves circulation and reduces swelling. Strength training builds muscle and supports healthy metabolic functions. The Physical Activity Guidelines for Americans from the U.S. Centers for Disease Control and Prevention recommends that adults engage in at least 150 minutes of moderate-intensity physical activity per week, 75 minutes of vigorous-intensity activity, or a combination of both.2 Always consult with a medical professional or healthcare provider before beginning any exercise, fitness, diet, or nutrition routine.
  3. Diet and hydration. A balanced diet rich in fruits and vegetables, lean proteins, whole grains, and healthy fats benefits overall health while reducing inflammation. Be sure to include anti-inflammatory foods such as fish, berries, leafy greens, nuts, seeds, turmeric, and ginger. Avoid inflammatory foods such as sugary beverages and refined carbohydrates, as well as foods high in trans fats and saturated fats. Additionally, drink plenty of water and limit sodium intake to stay hydrated and minimize fluid retention.

Additional strategies that may help reduce symptoms:

  • Use compression socks to reduce swelling in the ankles and feet.
  • Wear supportive, comfortable shoes that are properly sized.
  • Get plenty of rest with a goal of sleeping six to eight hours each night.
  • Consider massage therapy to improve circulation.
  • Always consult a healthcare provider before implementing major lifestyle changes.

The best strategy for reducing swelling and inflammation in people with hypothyroidism incorporates multiple approaches, including proper thyroid medication, regular exercise, making dietary changes, and staying hydrated. Additionally, wearing appropriate clothing and footwear, sleeping for six to eight hours per night, and massage therapy can assist with increasing circulation. Combining these approaches with the guidance of a healthcare provider may help improve overall health and minimize unwanted symptoms of hypothyroidism.

REFERENCE: 1. Mancini A, Di Segni C, Raimondo S, Olivieri G, Silvestrini A, Meucci E, Currò D. Thyroid Hormones, Oxidative Stress, and Inflammation. Mediators Inflamm. 2016;2016:6757154. doi: 10.1155/2016/6757154. Epub 2016 Mar 8. PMID: 27051079; PMCID: PMC4802023. 2. Centers for Disease Control and Prevention. (n.d.). Physical activity basics: Guidelines for adults. U.S. Department of Health & Human Services. Retrieved September 4, 2024, from https://www.cdc.gov/physical-activitybasics/guidelines/adults.html

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Note that DTE products, including NP Thyroid®, have not been reviewed by the FDA for safety or efficacy.

IMPORTANT RISK INFORMATION, INCLUDING BOXED WARNING & INDICATIONS
Important Risk Information

Drugs with thyroid hormone activity, alone or together with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects.
  • NP Thyroid® is contraindicated in patients with uncorrected adrenal insufficiency, untreated thyrotoxicosis, and hypersensitivity to any component of the product.
  • In the elderly and in patients with cardiovascular disease, NP Thyroid® should be used with greater caution than younger patients or those without cardiovascular disease.
  • Use of NP Thyroid® in patients with diabetes mellitus or adrenal cortical insufficiency may worsen the intensity of their symptoms.
  • The therapy of myxedema coma requires simultaneous administration of glucocorticoids.
  • Concomitant use of NP Thyroid® with oral anticoagulants alters the sensitivity of oral anticoagulants. Prothrombin time should be closely monitored in thyroid-treated patients on oral anticoagulants.
  • In infants, excessive doses of NP Thyroid® may produce craniosynostosis.
  • Partial loss of hair may be experienced by children in the first few months of therapy but is usually transient.
  • Adverse reactions associated with NP Thyroid® therapy are primarily those of hyperthyroidism due to therapeutic overdosage.
  • Many drugs and some laboratory tests may alter the therapeutic response to NP Thyroid ®. In addition, thyroid hormones and thyroid status have varied effects on the pharmacokinetics and actions of other drugs. Administer at least 4 hours before or after drugs that are known to interfere with absorption. Evaluate the need for dose adjustments when regularly administering within one hour of certain foods that may affect absorption.
  • NP Thyroid® should not be discontinued during pregnancy, and hypothyroidism diagnosed during pregnancy should be promptly treated.

Indications

NP Thyroid® (thyroid tablets, USP) is a prescription medicine that is used to treat a condition called hypothyroidism from any cause, except for cases of temporary hypothyroidism, which is usually associated with an inflammation of the thyroid (thyroiditis). It is meant to replace or supplement a hormone that is usually made by your thyroid gland.

NP Thyroid® is also used in the treatment and prevention of normal functioning thyroid goiters, such as thyroid nodules, Hashimoto’s thyroiditis, multinodular goiter, and in the management of thyroid cancer.
Revised 10/2023

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